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The Centre for HIV and AIDS Prevention Studies (CHAPS) is a South African non-governmental organisation (NGO) which has been implementing and disseminating evidence-based approaches to prevent the spread of HIV in Southern Africa. CHAPS is most recognised for pioneering work in researching and promoting the scale up of medical male circumcision for HIV prevention (MMC) in South Africa and the region CHAPS aims to provide a friendly and convenient environment for men to access a variety of healthcare services.

In 2005, ground breaking research in Orange Farm demonstrated how HIV could be prevented by medical male circumcision (MMC) when offered as part of a comprehensive HIV prevention strategy. This led CHAPS to launch the Bophelo Pele Male Circumcision Project in 2008. The Bophelo Pele project recently reached the major milestone of 20,000 safe medical male circumcisions (estimated to have prevented between 3000-4000 new HIV infections), as part of a national HIV prevention strategy in Orange Farm. CHAPS has since 2010 started more clinics and together these clinics have to date done more than 60,000 MMCs. CHAPS is one of largest NGOs focused on medical male circumcision for HIV prevention on the African continent.